Sildenafil is a widely used medication for the treatment of erectile dysfunction (ED), a condition where a man has difficulty achieving or maintaining an erection. It belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors, which work by increasing blood flow to the penis during sexual stimulation. Originally developed for heart-related chest pain, Sildenafil gained worldwide recognition under the brand name Viagra®, and has since become one of the most prescribed ED treatments globally. The medication begins to work within 30 to 60 minutes and its effects typically last for 4 to 6 hours, depending on the individual. Sildenafil is most effective when taken on an empty stomach about an hour before sexual activity. It does not cause an erection without sexual arousal.